In addition, Li et al. have disclosed that the upregulation of PI3K/AKT pathway encourages the expressions of placental growth issue (PlGF) and C-X-C Motif Chemokine Ligand one (CXCL1) in lung cancer stem cells, which even further stimulate angiogenesis [fifty nine]. CCPlenty of paracrine elements secreted by MSCs are ligands for receptors that act
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